This review does a good job of summarizing my thoughts after my two weeks with a Verizon Wireless Galaxy Nexus.
The only things I’d add to it:
1. John Gruber has repeatedly stated his opinion that the small 3.5” screen of the iPhone is perfect, that it doesn’t need to be any bigger, and if it were, it’d inhibit one-handed operation. I didn’t think this was such a big deal — until the GN. Having to continually swap between one-handed and two-handed usage when using the GN really annoyed me.
2. The positions of the volume and power buttons are really aggravating. As a right-handed user, I grip the phone with my left hand — which happen to land on both the volume buttons and power buttons, so I would frequently turn off the device or adjust the volume accidentally.
3. The formerly-useful menu button is gone. Or rather, it’s either at the bottom of the screen or at the top, depending on the app. It’s even different between Google apps.